COBRE Award Announcement

NIH/NIGHMS Center of Biomedical Research Excellence

Center for Redox Biology and Cardiovascular Disease

LSU Health Shreveport has been awarded a five-year, $10.5 million Centers of Biomedical Research Excellence (COBRE) grant by the National Institutes of Health.

The NIH’s COBRE initiative aims to strengthen an institution’s biomedical research infrastructure through the establishment of a thematic multi-disciplinary center. The $10,580,176 grant will fund the Center for Redox Biology and Cardiovascular Disease project at LSUHS and promote research on campus in the redox regulation of cardiovascular disease.

Cardiovascular disease is the leading cause of death and disability in the United States, and Louisiana ranks in the top five of states most affected by cardiovascular disease.  The COBRE Center for Redox Biology and Cardiovascular Disease will advance understanding of redox biology control of heart and vascular disease processes that may lead to new and better ways to detect or treat cardiovascular disease.

The Center for Cardiovascular Diseases and Sciences at LSU Health Shreveport has assembled investigators with advanced knowledge and research expertise across several departments to address redox biology mechanisms contributing to cardiovascular disease.  The principal investigator of the project is Dr. Chris Kevil, Vice Chancellor for Research and a Professor in the Department of Pathology. Key research personnel include: Dr. Christopher Pattillo, Assistant Professor in the Department of Molecular and Cellular Physiology; Dr. Manikandan Panchatcharam, Assistant Professor in the Department of Cellular Biology and Anatomy; and Dr. Hyung Nam, Assistant Professor in the Department of Pharmacology, Toxicology and Neuroscience.

Dr. Wayne Orr, Director of the Center for Cardiovascular Diseases and Sciences, Dr. Karen Stokes, Assistant Director of the Center for Cardiovascular Diseases and Sciences, and Dr. Andrew Yurochko, a Professor and member of the Centers Research Committee, were also instrumental in helping to secure the COBRE grant.

The Center for Redox Biology and Cardiovascular Disease is supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number P20GM121307.