Malcolm Feist Translational Research Grant in Cardiovascular Diseases

Applications can be received at any time during the year.

Malcolm Feist Translational Research Grant in Cardiovascular Diseases

Objective: The Board of Directors of the Center for Cardiovascular Diseases and Sciences (CCDS) seeks to encourage research in cardiovascular diseases that translate the findings in basic research into medical practice. The goal of this program is to transform scientific discoveries arising from laboratory studies into clinical applications that reduce the incidence, morbidity, and mortality of cardiovascular diseases.

Target Audience: Proposals are encouraged from clinical trainees and junior faculty in all clinical disciplines of relevance to cardiovascular diseases. Preference will be given to applicants who partner with a basic science researcher and whose research plan is directed towards extending a biomedical paradigm developed in a basic laboratory to the clinical setting.

Budget: The total annual budget cannot exceed $50,000. The initial application should include a budget for each project year of proposed support as well as a cumulative budget. Project support can be secured for up to 3 years, contingent upon research progress and productivity. The cumulative budget cannot exceed $150,000 ($50,000 per year).

Duration of support: The proposed research plan may cover a period of 1, 2 or 3 years. The initial application should specify the total length of the project, with corresponding budgets for each project year, as well as a cumulative budget. The duration of funding should reflect the amount of work proposed. For example, applicants proposing three-year projects should prepare a research plan reflecting three years of work. Projects are funded in 1-year increments. The Board can renew a Translational Grant twice, for a total funding period of 3 years. Continued funding by the Board in years 02 and 03 is contingent upon the applicant’s productivity and progress on the project. Renewals will be based on a progress report submitted to CCDS Board within 3 months of the next activation date.

Submission: Application forms and instructions are available on the Office of Research home page ( and in room F1-51 of the BRI. Research projects involving animals or human subjects must be approved by the IACUC or IRB, respectively, prior to submission of the grant application. A copy of the approved IACUC or IRB protocol (and informed consent form) must accompany the application. New applications will be limited to 10 single-spaced pages and the research plan shall include the following sections: specific aims, background/significance, and research design/methods. The bibliography (up to 2 pages) is not included in the 10-page limit. The application should also include biosketches for the principal investigator and co-investigators. Applications submitted by a trainee should include a letter from the faculty sponsor that outlines the roles of the trainee and sponsor in the research project, and outlines how the project will contribute toward the training and career development of the applicant. The Department Head or fellowship program director should also provide a letter that outlines a practical plan and time-line for the trainee’s participation in the project. Renewal applications (limited to 3-pages) should include a summary of progress towards completion of the project in the previous funding period. Evidence of continued IRB/IACUC approval for the project should be provided. New and renewal applications should be submitted to the Office of Sponsored Programs.

Evaluation: Applications will be reviewed by the CCDS Board of Directors (possibly with the assistance of relevant experts not serving on the Board). Priority for funding will be based on the qualifications of the applicant(s), the scientific and clinical merits of the proposed work, and relevance to cardiovascular diseases.   Applicants are encouraged to review the Malcolm Feist Translational Research Grant Peer Review Form prior to submitting their application. All applicants will receive a copy of their final Peer Review Forms.